高纯半绝缘SiC电阻率影响因素

采用物理气相传输(PVT)法进行高纯半绝缘SiC晶体生长,利用高温真空解吸附以及在系统中通入HCl和H2的方法,有效降低了系统中N、B和Al等杂质的背景浓度。使用二次离子质谱(SIMS)对晶体中杂质浓度测试,N、B和Al浓度分别小于1×1016、1×1015和2×1014 cm-3。对加工得到的晶片进行测试,全片的电阻率均在1×1010Ω·cm以上,微管密度小于0.02 cm-2,(004)衍射面的X射线摇摆曲线半高宽为34″。结果表明,该方法可以有效降低SiC晶体中N、B和Al等杂质浓度,提升SiC晶片的电阻率。使用该方法成功制备了4英寸(1英寸=2.54 cm)高纯半绝缘4H-SiC晶体。     

一种北斗联合低轨星座的导航增强方法研究

单纯依靠北斗导航系统提供定位导航授时服务,存在卫星信号落地功率低、易受遮蔽和阻断的不足。针对此问题,研究了一种北斗联合低轨星座实现导航增强的系统架构;提出了一种新的适应严重遮蔽或干扰条件下,基于到达时间(TOA)和到达频率(FOA)联合观测的定位解算算法;对高中低轨混合星座条件下的覆盖特性和精度衰减因子进行了仿真分析。分析结果表明,用户可见星数平均增加了64.2%,位置精度衰减因子(PDOP)平均改善了28.7%。研究结果可为下一代北斗的论证设计与研制建设提供参考借鉴。     

Robustness analysis and distributed control of a networked system with time-varying delays

This paper is concerned with the robustness analysis and distributed output feedback control of a networked system with uncertain time-varying communication delays. This system consists of a collection of linear time-invariant subsystems that are spatially interconnected via an arbitrary directed network. Using a dissipation inequality that incorporates dynamic hard IQCs (integral quadratic constraints) for the delay uncertainties, we derive some sufficient robustness conditions in the form of coupled linear matrix inequalities, in which the coupled parts reflect the interconnection structure of the system. We then provide a procedure to construct a distributed controller to ensure the robust stability of the closed-loop system and to achieve a prescribed $\ell_2$-gain performance. The effectiveness of the proposed approach is demonstrated by some numerical examples.     

Effect of the sintering temperature on microstructure and properties of Al2O3–Cu–Ni hybrid composites obtained by PPS

In the present research, the influence of sintering temperature on the microstructure and properties of Al₂O₃–Cu–Ni hybrid composites prepared by the Pulse Plasma Sintering (PPS) technique were described. In this research, three temperatures have been selected: 1250°C, 1300°C, and 1350°C. SEM observations were carried out to determine the distribution of the metallic phase in the composite depending on the sintering temperature. The conducted experiments and microscopic observations enabled a better understanding of the phenomena occurring between the ceramic matrix and metallic phase in the obtained materials. The mechanical properties like a hardness and fracture toughness were measured. The technology applied allowed us to obtain ceramic-metal composites with a homogeneous microstructure. It was found that the sintering temperature influences the selected physical and mechanical properties of the composites produced. It was found that samples produced at 1300°C are characterized by the highest relative density and the mechanical properties.     

Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1α-NF-κB Crosstalk In Vitro and In Vivo

Phorbol 12-myristate 13-acetate (PMA) is a potent tumor promoter and highly inflammatory in nature. Here, we investigated the toxic effects of PMA on different model system. PMA (10 μg) caused chromosomal aberrations on the Allium cepa root tip and induced mitotic dysfunction. Similarly, PMA caused embryonic and larval deformities and a plummeted survivability rate on zebrafish embryo in a dose-dependent manner. Persistently, PMA treatment on immortalized human keratinocyte human keratinocyte (HaCaT) cells caused massive inflammatory rush at 4 h and a drop in cell survivability at 24 h. Concomitantly, we replicated a cutaneous inflammation similar to human psoriasis induced by PMA. Herein, we used tangeretin (TAN), as an antagonist to counteract the inflammatory response. Results from an in vivo experiment indicated that TAN (10 and 30 mg/kg) significantly inhibited PMA stimulated epidermal hyperplasia and intra-epidermal neutrophilic abscesses. In addition, its treatment effectively neutralized PMA induced elevated reactive oxygen species (ROS) generation on in vitro and in vivo systems, promoting antioxidant response. The association of hypoxia-inducible factor 1-alpha (HIF-1α)-nuclear factor kappa-light-chain-enhancer of activated b cells (NF-κB) crosstalk triggered by PMA enhanced PKCα-ERK1/2-NF-κB pathway; its activation was also significantly counteracted after TAN treatment. Conclusively, we demonstrated TAN inhibited the nuclear translocation of HIF-1α and NF-κB p65. Collectively, TAN treatment ameliorated PMA incited malignant inflammatory response by remodeling the cutaneous microenvironment.     

Fucoidans as Potential Therapeutics for Age-Related Macular Degeneration—Current Evidence from In Vitro Research

Age-related macular degeneration (AMD) is the major reason for blindness in the industrialized world with limited treatment options. Important pathogenic pathways in AMD include oxidative stress and vascular endothelial growth factor (VEGF) secretion. Due to their bioactivities, fucoidans have recently been suggested as potential therapeutics. This review gives an overview of the recent developments in this field. Recent studies have characterized several fucoidans from different species, with different molecular characteristics and different extraction methods, in regard to their ability to reduce oxidative stress and inhibit VEGF in AMD-relevant in vitro systems. As shown in these studies, fucoidans exhibit a species dependency in their bioactivity. Additionally, molecular properties such as molecular weight and fucose content are important issues. Fucoidans from Saccharina latissima and Laminaria hyperborea were identified as the most promising candidates for further development. Further research is warranted to establish fucoidans as potential therapeutics for AMD.     

[数据驱动的智能服务]数据驱动的复杂产品智能服务技术与应用

随着传感器、数据采集装置和其他具备感知能力的模块在复杂产品服务运行阶段的应用，复杂产品运维系统的数字化和智能化程度越来越高，具有实时、多源、异构、海量等特性的数据成为提高复杂产品系统可靠和低成本运行的决策依据，数字孪生技术提供了一种有效途径。介绍了数据驱动的复杂产品智能服务研究进展；分析了数据驱动的智能服务基本特征与框架模型；提出了数据驱动的复杂产品智能服务方法，主要包括面向服务的复杂产品建模与仿真方法、数据驱动的服务需求获取与精准分析预测方法、基于数字孪生的设备故障识别与动态性能预测方法、数据驱动的装备视情维修与备件库存联合多目标决策优化方法、基于数字孪生的复杂产品辅助维修技术、多要素协同的复杂装备能效精准分析预测方法、基于数据挖掘的复杂产品运行优化控制方法等；给出了智能服务系统的应用案例。所提出的框架和方法可为现代制造服务的智能化转型升级提供参考。     

磁流变减振器魔术公式模型在悬架控制中的应用

基于某款磁流变减振器特性实验数据，辨识了磁流变减振器魔术公式模型的各项参数，模型误差在8%以内。在适当简化磁流变减振器魔术公式模型的条件下，通过直接逆推得到磁流变减振器魔术公式逆模型。仿真中，磁流变减振器魔术公式正、逆模型实现加速度驱动阻尼控制策略期望阻尼力的误差平均值为3.67%。台架实验中，磁流变减振器魔术公式逆模型的应用使车身加速度降低了6.27%，实现了加速度驱动阻尼控制策略的控制效果。磁流变减振器魔术公式模型在半主动控制悬架系统仿真及台架实验中的成功应用对磁流变半主动悬架控制系统的研究有较强的实际意义。     

基于深度语义分割的多源遥感图像海面溢油监测

针对遥感图像海面溢油区域通常受到斑噪声以及强度不均等因素的影响,从而导致溢油区域监测效果较差的问题,本文引入了深度语义分割的方法,将深度卷积神经网络与全连接条件随机场相结合,形成端对端连接。以Resnet结构为基础,首先通过深度卷积神经网络对多源遥感图像粗分割并作为输入,然后经过改进的全连接条件随机场,利用高斯成对势和平均场近似定理,建立条件随机场形成递归神经网络作为输出。通过多源遥感图像对海面溢油区域进行监测,并利用可见光图像估计溢油区域面积。实验在所建立的多源遥感图像数据集上与其它先进模型进行对比,结果表明本文方法提高了溢油区域的分割精度以及精细细节程度,平均交并比为82.1%,监测效果具有明显地改善。     

原子及近原子尺度制造——制造技术发展趋势

探讨了制造技术发展趋势，论述了制造历史发展的三个阶段，指出原子及近原子尺度制造（ACSM）是下一代制造技术的主流发展趋势，对未来科技发展和高端元件制造具有重要意义。详细分析阐述了ACSM的主要研究内容及关键科学问题，并提出了相应的建议和措施。